sraeli Researchers Discover That Cholesterol-Lowering Drug Fenofibrate (Tricor) Could Downgrade COVID-19 Severity

[Assam_Bhayya]

COVID-19 Drugs: Israeli Researchers Discover That Cholesterol-Lowering Drug Fenofibrate (Tricor) Could Downgrade COVID-19 Severity

Source: COVID-19 Drugs  Jul 16, 2020  3 days ago

COVID-19 Drugs: A research team led by Hebrew University of Jerusalem (HU)'s Professor Dr Yaakov Nahmias says that a simple and inexpensive cholesterol-lowering drug called Fenofibrate (Tricor) that is been approved and on the market for decades could help downgrade the severity of COVID-19 disease.

The early research finding which looks promising has been published in the preprint section of the Journal: Cell in a column called Cell Press Sneak Peak while it is being peer-reviewed. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3650499
 
In the last three months, Dr Nahmias and Dr Benjamin tenOever at New York's Icahn School of Medicine at Mount Sinai have focused on the ways in which the SARS-CoV-2 changes patients' lungs in order to reproduce itself.
 
Among their major findings is the fact that the novel coronavirus prevents the routine burning of carbohydrates. As a result, large amounts of fat accumulate inside lung cells, a condition the virus needs in order to reproduce. This new understanding of SARS CoV-2 may help explain why patients with high blood sugar and cholesterol levels are often at a particularly high risk to develop COVID-19.
 
Typically viruses are parasites that lack the ability to replicate on their own, so they take control of host cells to help accomplish that task.
 
Dr Nahmias explained to Thailand Medical News, "By understanding how the SARS-CoV-2 controls our metabolism, we can wrestle back control from the virus and deprive it from the very resources it needs to survive."
 
Armed with this information in hand, Dr Nahmias and Dr tenOever began to screen FDA-approved medications that interfere with the virus' ability to reproduce.
 
Significantly, in lab studies, the cholesterol-lowering drug Fenofibrate (Tricor) showed extremely promising results. By allowing lung cells to burn more fat, fenofibrate breaks the virus' grip on these cells, and prevents SARS CoV-2's ability to reproduce. In fact, within only five days of treatment, the virus almost completely disappeared.
 
Dr Nahmias added, "With second-wave infections spiking in countries across the globe, these findings could not come at a better time, and global cooperation may provide the cure.”
 
Dr tenOever added, "The collaboration between the Nahmias and tenOever labs demonstrates the power of adopting a multi-disciplinary approach to study SARS-CoV-2 and that our findings could truly make a significant different in reducing the global burden of COVID-19."
 
Though there are many international efforts currently underway to develop a coronavirus vaccine, studies suggest that vaccines may only protect patients for a few months.
 
Hence it is therefore critical to find a way to block the coronavirus' ability to function, rather than neutralizing its ability to strike in the first place and such an approach may be the key to turning the tables on COVID-19.
 
Dr Nahmias concluded, "If our findings are borne out by clinical studies, this course of treatment could potentially downgrade COVID-19's severity into nothing worse than a common cold."

[Silverado]

@ramdevbaba Goru eti Andi ,e Assam Goru Edo Edo antunaru ,coronil medicine undaga

Randi vachi

 

[Assam_Bhayya]

Ante andharini intlo kurchopetti, stress ku subjected ayyetattu chesi, bayata thiginaa mask petukunte lower oxygen levels tho, totall ga metabolism dobbetti lipids level hike chesi, common cold virus severity ni pencharu anamaata

 

 

Andhuke kadha ra, Jan lo enter ayina virus, Feb, Mar, Apr, May lo kuda case lu levu, saavu lu leevu, lockdown petti bayapetti, lockdown ethinaaka, mask pettukuni thiriginaa(at least 30 to 40% wearing mask now after lockdown lifting) cases inka inka peruguthunnayi 

 

 

Call me a COVIDIOT association pesident, but its a bitter truth you'll realize very very sooner

[Assam_Bhayya]

      

 

https://www.eenadu.net/latestnews/general/0600/120086887

 

[Silverado]

3 minutes ago, Assam_Bhayya said:

Ante andharini intlo kurchopetti, stress ku subjected ayyetattu chesi, bayata thiginaa mask petukunte lower oxygen levels tho, totall ga metabolism dobbetti lipids level hike chesi, common cold virus severity ni pencharu anamaata

 

 

Andhuke kadha ra, Jan lo enter ayina virus, Feb, Mar, Apr, May lo kuda case lu levu, saavu lu leevu, lockdown petti bayapetti, lockdown ethinaaka, mask pettukuni thiriginaa(at least 30 to 40% wearing mask now after lockdown lifting) cases inka inka peruguthunnayi 

 

 

Call me a COVIDIOT association pesident, but its a bitter truth you'll realize very very sooner

 

[Silverado]

2 minutes ago, Assam_Bhayya said:

      

 

https://www.eenadu.net/latestnews/general/0600/120086887

 

Ithe ipudu eti seyamantar andi

[Assam_Bhayya]

1 minute ago, Silverado said:

Ithe ipudu eti seyamantar andi

We just need to live our life, removing karrona from our mind, the word should be banned to be used by and in any media, thats all, problems anni solve ayithayi. . '

[Silverado]

1 minute ago, Assam_Bhayya said:

We just need to live our life, removing karrona from our mind, the word should be banned to be used by and in any media, thats all, problems anni solve ayithayi. . '

Saana baga separu Andi ,iroju nunche nen follow avtha Andi ,k na Andi

Meeru already start sesara andi

[Assam_Bhayya]

India lo Mar-25th ku start anukunta lockdown, Mar1 to Mar25, 25 days janalu theatres, gyms lo, tirumala laanti temples lo crowded without masks. . atleast appatiki infect ayina sarey, April lo May lo ayina cases undali, deaths undali kaadaaa

Lockdown lo infections baaga spread avvadam endhoo 

 

[Silverado]

Calling @Modi Goru to ban corona word in India andi.,begaa sesai andeee...

[Silverado]

1 minute ago, Assam_Bhayya said:

India lo Mar-25th ku start anukunta lockdown, Mar1 to Mar25, 25 days janalu theatres, gyms lo, tirumala laanti temples lo crowded without masks. . atleast appatiki infect ayina sarey, April lo May lo ayina cases undali, deaths undali kaadaaa

Lockdown lo infections baaga spread avvadam endhoo 

 

Anthe nandi ,adhi Corona purugu plan Andi manaki eti telusatdi Andi ,symptoms ipudu supistundamo dikkumalina purugu 

 

[Sreeven]

49 minutes ago, Assam_Bhayya said:

India lo Mar-25th ku start anukunta lockdown, Mar1 to Mar25, 25 days janalu theatres, gyms lo, tirumala laanti temples lo crowded without masks. . atleast appatiki infect ayina sarey, April lo May lo ayina cases undali, deaths undali kaadaaa

Lockdown lo infections baaga spread avvadam endhoo 

 

Argentina ship News chudu pichekkiddi..anni precautions teesukuni pampina andariki corona vachindi..

[Assam_Bhayya]

2 hours ago, Sreeven said:

Argentina ship News chudu pichekkiddi..anni precautions teesukuni pampina andariki corona vachindi..

viney vallam manam erripuvvulam kadha bedaru e medical/pharma media gallaku, aallu cheppina sollu last 6-7 months lo  anthaa inthaa kaadu, inka vintu kurchunte, last year lo ISS ku vellina astronaut ku, mars medha ku vella vaadiki ikkadinundi space shippu lo karrona kit pampisthe positive ochindhi ani cheppina cheptharu wait cheyi, drama inka inka untadhi. .  

 

[Sreeven]

18 minutes ago, Assam_Bhayya said:

viney vallam manam erripuvvulam kadha bedaru e medical/pharma media gallaku, aallu cheppina sollu last 6-7 months lo  anthaa inthaa kaadu, inka vintu kurchunte, last year lo ISS ku vellina astronaut ku, mars medha ku vella vaadiki ikkadinundi space shippu lo karrona kit pampisthe positive ochindhi ani cheppina cheptharu wait cheyi, drama inka inka untadhi. .  

 

Ala aithe vallalo antha mandiki corona symptoms ela vachayi..intha mandi ela chani potunnaru..medical pharma companies stories telusu idi konchem danger gane vundi