Why FDA doesn't regulate supplements? Big Pharma co sucks

[Beardman]

https://clinicaltrials.gov/ct2/show/NCT00977353

Major depressive disorder is a complex disease and most currently available antidepressants aiming at monoamine neurotransmission exhibit limited efficacy and cognitive effects. N-methyl-D-aspartate (NMDA), one subtype of glutamate receptors, plays an important role in learning and memory. N-methyl-D-aspartic acid (NMDA) enhancing agents, such as sarcosine (N-methylglycine), have been used as adjunctive therapy of schizophrenia. Sarcosine improved not only psychotic but also depressive symptoms in patients with schizophrenia. To confirm its antidepressant effect, the purpose of this study is to compare citalopram and sarcosine in efficacy for major depressive patients.

 

Detailed Description:

Major depressive disorder is a complex disease and most currently available antidepressants aiming at monoamine neurotransmission exhibit limited efficacy and cognitive effects. Novel therapies via manipulating other neurotransmission (e.g. glutamate receptor) are being developed.

NMDA enhancing agents, such as sarcosine have been demonstrated to improve negative symptoms and depressive symptoms of schizophrenic patients. The purpose of this study is to compare citalopram and sarcosine in aspects of efficacy, safety in major depressive patients.

In the study, 40 major depressive patients are recruited into the 6-week trial and randomly assigned into the two groups (20-60 mg/d citalopram, or 500 - 1500 mg/d sarcosine) with a double-blind manner. Hamilton Depression Rating Scale(17-item), CGI(Clinical Global Impression), GAF(Global Assessment of Function)and side effects are evaluated every two weeks during the trial. The efficacies of two groups are compared.

[soodhilodaaram]

4 minutes ago, Beardman said:

https://clinicaltrials.gov/ct2/show/NCT00977353

Major depressive disorder is a complex disease and most currently available antidepressants aiming at monoamine neurotransmission exhibit limited efficacy and cognitive effects. N-methyl-D-aspartate (NMDA), one subtype of glutamate receptors, plays an important role in learning and memory. N-methyl-D-aspartic acid (NMDA) enhancing agents, such as sarcosine (N-methylglycine), have been used as adjunctive therapy of schizophrenia. Sarcosine improved not only psychotic but also depressive symptoms in patients with schizophrenia. To confirm its antidepressant effect, the purpose of this study is to compare citalopram and sarcosine in efficacy for major depressive patients.

 

Detailed Description:

Major depressive disorder is a complex disease and most currently available antidepressants aiming at monoamine neurotransmission exhibit limited efficacy and cognitive effects. Novel therapies via manipulating other neurotransmission (e.g. glutamate receptor) are being developed.

NMDA enhancing agents, such as sarcosine have been demonstrated to improve negative symptoms and depressive symptoms of schizophrenic patients. The purpose of this study is to compare citalopram and sarcosine in aspects of efficacy, safety in major depressive patients.

In the study, 40 major depressive patients are recruited into the 6-week trial and randomly assigned into the two groups (20-60 mg/d citalopram, or 500 - 1500 mg/d sarcosine) with a double-blind manner. Hamilton Depression Rating Scale(17-item), CGI(Clinical Global Impression), GAF(Global Assessment of Function)and side effects are evaluated every two weeks during the trial. The efficacies of two groups are compared.

em cheppalanukuntunnavu gaddapoda 

[Beardman]

19 minutes ago, soodhilodaaram said:

em cheppalanukuntunnavu gaddapoda 

One of the best supplement  not approved medically despite treating symptoms, instead doctors prescribe Benzodiazepenes. But why?

[Scada]

.

[soodhilodaaram]

36 minutes ago, Beardman said:

One of the best supplement  not approved medically despite treating symptoms, instead doctors prescribe Benzodiazepenes. But why?

medicines that can only treat symptoms can expand the economy wheres as one time fixes dont really contribute to economy..health being the biggest industry past defence, pharma and wars are critical piece of economy

people expect others to help them, fact is why would they.. it could be govt or doctors, their job is to protect their interests. not yours

unless people research a health issues themselves, the world is not going to fix anything for them

[Beardman]

1 minute ago, Scada said:

Is it ON ?

What's ON?

[Beardman]

2 minutes ago, soodhilodaaram said:

medicines that can only treat symptoms can expand the economy wheres as one time fixes dont really contribute to economy..health being the biggest industry past defence, pharma and wars are critical piece of economy

What do you mean by one time fix?

[soodhilodaaram]

2 minutes ago, Beardman said:

What do you mean by one time fix?

one time fix means those that treat the disease itself for good.. not the symptoms.. the disease does likely come back.. for example surgery is one such practice that fixes the issue

 

[Beardman]

8 minutes ago, soodhilodaaram said:

medicines that can only treat symptoms can expand the economy wheres as one time fixes dont really contribute to economy..health being the biggest industry past defence, pharma and wars are critical piece of economy

people expect others to help them, fact is why would they.. it could be govt or doctors, their job is to protect their interests. not yours

unless people research a health issues themselves, the world is not going to fix anything for them

How can an ill person do online research being under the control of monster drugs like benzo's. It sucks

[Beardman]

1 minute ago, soodhilodaaram said:

one time fix means those that treat the disease itself for good.. not the symptoms.. the disease does likely come back.. for example surgery is one such practice that fixes the issue

 

There is no medicine that cures certain mental health disorders, but they treat the symptoms. 

No difference between a supplement like sarcosine and drug like benzo. Benzos are the poision pills, dont know why they are prescribed.

[Beardman]