cellphone Posted May 8, 2021 Report Share Posted May 8, 2021 DRDO along with its industry partner Dr Reddy’s Laboratories (DRL, Hyderabad) started the clinical trials to test the safety and efficacy of the drug in COVID-19 patients. In Phase-II trials (including dose ranging) conducted during May to October 2020, the drug was found to be safe in Covid-19 patients, and showed significant improvement in their recovery. Phase IIa was conducted in six hospitals and Phase IIb (dose ranging) clinical trial was conducted at 11 hospitals all over the country. Phase-II trial was conducted on 110 patients. In efficacy trends, the patients treated with 2-DG showed faster symptomatic cure than Standard of Care (SoC) on various endpoints. A significantly favourable trend (2.5 days difference) was seen in terms of the median time to achieving normalization of specific vital signs parameters when compared to SOC. Based on successful results, DCGI further permitted the Phase-III clinical trials in November 2020. The Phase-III clinical trial was conducted on 220 patients during Dec 2020 to March 2021 on a large number of patients at 27 Covid hospitals situated in states of Delhi, UP, West Bengal, Gujrat, Rajasthan, Maharashtra, Andhra Pradesh, Telangana, Karnataka and Tamil Nadu. The detailed data of phase-III clinical trials was presented to DCGI. “In 2-DG arm, a significantly higher proportion of patients improved symptomatically and became free from supplemental oxygen dependence (42 per cent vs 31 per cent) by Day-3 in comparison to SOC, indicating an early relief from Oxygen therapy/dependence. The similar trend was observed in patients more than 65 years also,” the release said. Quote Link to comment Share on other sites More sharing options...
jawaani_jaaneman Posted May 8, 2021 Report Share Posted May 8, 2021 220 patients in 27 hospitals... Quote Link to comment Share on other sites More sharing options...
cellphone Posted May 8, 2021 Author Report Share Posted May 8, 2021 Just now, jawaani_jaaneman said: 220 patients in 27 hospitals... lifted from wikipedia Quote Link to comment Share on other sites More sharing options...
karthik25 Posted May 18, 2021 Report Share Posted May 18, 2021 Quote Link to comment Share on other sites More sharing options...
jawaani_jaaneman Posted May 18, 2021 Report Share Posted May 18, 2021 Vaccine is time taking process...effectiveness ki chala time padtundi.. Hopefully this potlam is a game changer for India. Hospital infrastructure, beds and oxygen is an expensive and always in short ...long term la assalu maintain cheyalem. 1 Quote Link to comment Share on other sites More sharing options...
jawaani_jaaneman Posted May 18, 2021 Report Share Posted May 18, 2021 I think 10,000 packets distribute chesinaru anukunta last two days la Delhi la 1 Quote Link to comment Share on other sites More sharing options...
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