Covishield protection wanes after three months, Lancet study finds

[Kool_SRG]

The findings drawn from datasets in Brazil and Scotland suggest that booster programmes are needed in those vaccinated with AstraZeneca Covid vaccine, known as Covishield in India.

London: The protection offered by the Oxford-Astra Zeneca COVID-19 vaccine declines after three months of receiving two doses of the preventive, according to a study published in The Lancet journal.

The findings drawn from datasets in Brazil and Scotland suggest that booster programmes are needed to help maintain protection from severe disease in those vaccinated with AstraZeneca, known as Covishield in India.

The researchers analysed data for two million people in Scotland and 42 million people in Brazil who had been vaccinated with the AstraZeneca vaccine.

In Scotland, when compared with two weeks after receiving a second dose, there was approximately a fivefold increase in the chance of being hospitalised or dying from COVID-19 nearly five months after being double vaccinated, the researchers said.

The decline in effectiveness begins to first appear at around three months, when the risk of hospitalisation and death is double that of two weeks after the second dose, they said.

The researchers from Scotland and Brazil found that the risk of hospitalisation and death increases threefold just short of four months after the second vaccine dose. Similar numbers were seen for Brazil, they said.

“Vaccines have been a key tool in fighting the pandemic, but waning in their effectiveness has been a concern for a while,” said Professor Aziz Sheikh, from the University of Edinburgh, UK.

“By identifying when waning first starts to occur in the Oxford-AstraZeneca vaccine, it should be possible for governments to design booster programmes that can ensure maximum protection is maintained, Sheikh said.

The team was able to compare data between Scotland and Brazil as they had a similar interval between doses — 12 weeks — and initial prioritisation of who was vaccinated — people at highest risk of severe disease and healthcare workers.

The dominant variant was different in each country during the study period — Delta in Scotland and Gamma in Brazil.

This means the decline in effectiveness is likely because of vaccine waning and the impact of variants, according to the researchers.

The study also estimated vaccine effectiveness at similar fortnightly intervals by comparing outcomes of people who have been jabbed with those who are unvaccinated.

However, the experts warned that these figures should be treated with caution because it is becoming harder to compare unvaccinated people to those vaccinated with similar characteristics, particularly among older age groups where so many people are now vaccinated.

“Our analyses of national datasets from both Scotland and Brazil suggest that there is considerable waning of effectiveness for the Oxford AstraZeneca vaccine, with protection against severe COVID-19 falling over time,” said Professor Srinivasa Vittal Katikireddi from the University of Glasgow in the UK.

“Our work highlights the importance of getting boosters, even if you’ve had two doses of the Oxford AstraZeneca vaccine, as soon as you are able to,” Katikiredd added.

[Raven_Rayes]

okay. I'm fcuked. thanks.

[Kool_SRG]

Adhi idhi chupinchi twaralo booster dose is recommended antaaru...

[Aparichituduafdb]

1 hour ago, Kool_SRG said:

Adhi idhi chupinchi twaralo booster dose is recommended antaaru...

Nenu cheppa kada booster dose pakka ani 😊

[Aparichituduafdb]

Covidsheild monnane vesukunna 2nd dose inko 3months safe anamata but mandu kotta ade roju 😒

[Kool_SRG]

2 minutes ago, Aparichituduafdb said:

Nenu cheppa kada booster dose pakka ani 😊

Idoh pedha business ayipoyindhi...

[Raven_Raeyes]

booster ani mosam chesturru...idi booster endi inka...muchataga third dose anale..

for best results, yearly three doses...minimum recommended two doses...

wave ochinapudalla mad rush and demand..

monna ne papam adar poonawala dose production tagginchali,demand ledu anado ledo omicron punyama ani inko 2 billion doses gurantee

[Mingutha]

"Just give me 2 weeks, just weeks of your life, we'll flatten the curve. . . "

 

"The next 2 weeks is very very critical for the humanity to survive. . . ."

  

[TamrajKilvish]

Nadi Sputnik

[Kool_SRG]

20 hours ago, TamrajKilvish said:

Nadi Sputnik

[rapchik123]

ninna ne kada man 7+ months annaru , ofc this research is done by a pune based institute , so the results could be a little sketchy

https://timesofindia.indiatimes.com/india/covishield-cover-high-7-months-after-2-doses-90-antibody-prevalence-seen-study/articleshow/88365780.cms

[reality]

On 12/22/2021 at 5:26 AM, TamrajKilvish said:

Nadi Sputnik

Just wait for the news… repo mapo adhi kuda cheptharu…. Sputnik asalu Indian race pi antha effective kadhu ani….

Variant efficacy ayyindhi 

Duration efficacy ayyindhi

next race efficacy 

trash efficacy…. More to come 

manam ooooo koduthu eyinchukovadame… adhe..,, boooooster

[reality]

1 hour ago, rapchik123 said:

ninna ne kada man 7+ months annaru , ofc this research is done by a pune based institute , so the results could be a little sketchy

https://timesofindia.indiatimes.com/india/covishield-cover-high-7-months-after-2-doses-90-antibody-prevalence-seen-study/articleshow/88365780.cms

vaccines ammukovali kadha… vallu kuda bathakali kadha

[Kool_SRG]

6 minutes ago, reality said:

Just wait for the news… repo mapo adhi kuda cheptharu…. Sputnik asalu Indian race pi antha effective kadhu ani….

Variant efficacy ayyindhi 

Duration efficacy ayyindhi

next race efficacy 

trash efficacy…. More come 

manam ooooo koduthu eyinchukovadame… adhe..,, boooooster

Already comparisions have come Sputnik V & sputnik light offer better neutralization compared to Pfizer & Moderna

 

 

[reality]

Just now, Kool_SRG said:

Laready comparisions have come Sputnik V & sputnik light offer better neutralization compared to Pfizer & Moderna

 

 

Russia lo deaths ekkuva untunnayi mari, lately??